ATZ platform
Novel source of adult stem cells for regenerative medicine
The problem
New source of adult stem cells for regenerative medicine
The Curileum team has identified a new source of multipotent adult stem cells in the lower part of the gut for regenerative medicine.
Stem cells found at the transition zone of two developmental tissues – called the anorectal transition zone (ATZ) – have the capacity repair and restore function to damaged and diseased tissues.
Our scientists have demonstrated using in vivo models that ATZ stem cells heal perianal fistulas and generate new tissue in the liver and pancreas allogeneic (non-self) environments.
